TECHNOLOGY

Cross-linked SupraMolecular NanoParticle

Injection/tattoo delivery
 

EFFECTIVE DRUG CONCENTRATION

  • Nanoparticle gives controlled time release and drug encapsulation
  • Delivery with OnychoClear resulted in 60x the drug amount of topical cream in initial delivery
  • Measurable drug concentration persisted for 14 days vs. 2 days of topical cream
Our crosslinked supramolecular nanoparticles
 

ONYCHOMYCOSIS TREATMENT

  • Tattoo on fungal infected areas
  • Introduce OnychoClear onto tattooed areas
  • Intradermal drug retention probed by fluorescent signal
  • Finite intradermal retention and effective anti-fungal Rx
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LONGER INTRADERMAL RETENTION

  • c-SMNP cross-linked supramolecular nanoparticles stay in the skin longer than smaller-sized degradable nanoparticles
  • Cross-linked nanoparticles give the maximum concentration by anchoring

Targeted Diseases

NanoDerm is an effective and simple treatment against Onychomycosis and Keloid. OnychoClear can be easily administered via injection/tattooing, and is retained in the skin during a slow and controlled drug release.

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Onychoclear Application

  • Two step application includes a local anesthetic injection followed by a Onychoclear injection
  • Onychoclear is a reimbursable procedure
  • Podiatrist and Dermatologist incentives available
 
 

KeloClear Application

  • Locally applied corticosteroid-encapsulating nanoparticles have an increased drug lifetime and bioavailability which are the main limitations of current treatments
  • Podiatrist and Dermatologist incentives available

About

 NanoDerm Pharma is a spinoff company from the UCLA School of Medicine with both Federal and Private funding.

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